Misfolded alpha-synuclein detection by RT-QuIC in dementia with lewy bodies: a systematic review and meta-analysis

Misfolded alpha-synuclein detection by RT-QuIC in dementia with lewy bodies: a systematic review and meta-analysis

Introduction: Dementia with Lewy Bodies (DLB) is the second most common cause of neurodegenerative dementia after Alzheimer’s disease (AD), but the field is still lacking a specific biomarker for its core pathology: alpha synuclein (α-syn). Realtime quaking induced conversion (RT-QuIC) has recently...

Full description

Bibliographic Details
Main Authors: Carmen Peña-Bautista, Rakesh Kumar, Miguel Baquero, Jan Johansson, Consuelo Cháfer-Pericás, Axel Abelein, Daniel Ferreira
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
dementia with Lewy bodies
alpha-synuclein
RT-QuIC
biomarker
diagnosis
copathologies
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1193458/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1193458/full

Similar Items