The Interplay of Hypoxia Signaling on Mitochondrial Dysfunction and Inflammation in Cardiovascular Diseases and Cancer: From Molecular Mechanisms to Therapeutic Approaches

The Interplay of Hypoxia Signaling on Mitochondrial Dysfunction and Inflammation in Cardiovascular Diseases and Cancer: From Molecular Mechanisms to Therapeutic Approaches

Cardiovascular diseases (CVDs) and cancer continue to be the primary cause of mortality worldwide and their pathomechanisms are a complex and multifactorial process. Insufficient oxygen availability (hypoxia) plays critical roles in the pathogenesis of both CVDs and cancer diseases, and hypoxia-indu...

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Bibliographic Details
Main Authors: Esmaa Bouhamida, Giampaolo Morciano, Mariasole Perrone, Asrat E. Kahsay, Mario Della Sala, Mariusz R. Wieckowski, Francesco Fiorica, Paolo Pinton, Carlotta Giorgi, Simone Patergnani
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biology
Subjects:
hypoxia
HIF-1α
mitochondria
oxidative stress
inflammation
cardiovascular diseases
Online Access:https://www.mdpi.com/2079-7737/11/2/300

Internet

https://www.mdpi.com/2079-7737/11/2/300

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