Accuracy of diagnosis among clinical malaria patients: comparing microscopy, RDT and a highly sensitive quantitative PCR looking at the implications for submicroscopic infections

Accuracy of diagnosis among clinical malaria patients: comparing microscopy, RDT and a highly sensitive quantitative PCR looking at the implications for submicroscopic infections

Abstract Background The World Health Organization recommends parasitological confirmation of all suspected malaria cases by microscopy or rapid diagnostic tests (RDTs) before treatment. These conventional tools are widely used for point-of-care diagnosis in spite of their poor sensitivity at low par...

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Bibliographic Details
Main Authors: Stephen Opoku Afriyie, Thomas Kwame Addison, Yilekal Gebre, Abdul-Hakim Mutala, Kwasi Baako Antwi, Dawood Ackom Abbas, Kofi Agyapong Addo, Austine Tweneboah, Nana Kwame Ayisi-Boateng, Cristian Koepfli, Kingsley Badu
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Malaria Journal
Subjects:
Malaria
Microscopy
Rapid diagnostic test
varATS qPCR
Sensitivity
Online Access:https://doi.org/10.1186/s12936-023-04506-5

Internet

https://doi.org/10.1186/s12936-023-04506-5

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