Nicotinamide Mononucleotide Alleviates LPS-Induced Inflammation and Oxidative Stress via Decreasing COX-2 Expression in Macrophages

Nicotinamide Mononucleotide Alleviates LPS-Induced Inflammation and Oxidative Stress via Decreasing COX-2 Expression in Macrophages

Macrophage activation is an important process in controlling infection, but persistent macrophage activation leads to chronic inflammation and diseases, such as tumor progression, insulin resistance and atherosclerosis. Characterizing metabolic signatures of macrophage activation is important for de...

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Bibliographic Details
Main Authors: Jing Liu, Zhaoyun Zong, Wenhao Zhang, Yuling Chen, Xueying Wang, Jie Shen, Changmei Yang, Xiaohui Liu, Haiteng Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
inflammation
macrophage
nicotinamide mononucleotide
NAD
COX-2
prostaglandin E2
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.702107/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.702107/full

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