Beovu, but not Lucentis impairs the function of the barrier formed by retinal endothelial cells in vitro

Abstract Because rare, but severe adverse effects, i.e. retinal vasculitis or retinal vein occlusion, have been observed after repetitive intravitreal injections of VEGF-A-binding single-chain variable fragment brolucizumab (Beovu), we investigated its possible impact on the barrier formed by immort...

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Bibliographic Details
Main Authors: Heidrun L. Deissler, Catharina Busch, Armin Wolf, Matus Rehak
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-16770-7