Higher HIV-1 Env gp120-Specific Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity Is Associated with Lower Levels of Defective HIV-1 Provirus

Higher HIV-1 Env gp120-Specific Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity Is Associated with Lower Levels of Defective HIV-1 Provirus

A cure for HIV-1 (HIV) remains unrealized due to a reservoir of latently infected cells that persist during antiretroviral therapy (ART), with reservoir size associated with adverse health outcomes and inversely with time to viral rebound upon ART cessation. Once established during ART, the HIV rese...

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Bibliographic Details
Main Authors: Ryan Yucha, Morgan L. Litchford, Carolyn S. Fish, Zak A. Yaffe, Barbra A. Richardson, Elizabeth Maleche-Obimbo, Grace John-Stewart, Dalton Wamalwa, Julie Overbaugh, Dara A. Lehman
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Viruses
Subjects:
HIV-1
HIV reservoir
antibody-dependent cellular cytotoxicity (ADCC)
HIV provirus
pediatric HIV
CS-IPDA
Online Access:https://www.mdpi.com/1999-4915/15/10/2055

Internet

https://www.mdpi.com/1999-4915/15/10/2055

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