Drug targets regulate systemic metabolism and provide new horizons to treat nonalcoholic steatohepatitis

Drug targets regulate systemic metabolism and provide new horizons to treat nonalcoholic steatohepatitis

Nonalcoholic steatohepatitis (NASH), is the advanced stage of nonalcoholic fatty liver disease (NAFLD) with rapidly rising global prevalence. It is featured with severe hepatocyte apoptosis, inflammation and hepatic lipogenesis. The drugs directly targeting the processes of steatosis, inflammation a...

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Bibliographic Details
Main Authors: Yibing Wang, Hanhan Yu, Zhipeng Cen, Yutong Zhu, Wenyi Wu
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Metabolism Open
Subjects:
NASH
Drug targets
Mechanisms
Energy expenditure
Metabolic homeostasis
Drug discovery
Online Access:http://www.sciencedirect.com/science/article/pii/S2589936823000397

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http://www.sciencedirect.com/science/article/pii/S2589936823000397

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