Progranulin is expressed within motor neurons and promotes neuronal cell survival

<p>Abstract</p> <p>Background</p> <p>Progranulin is a secreted high molecular weight growth factor bearing seven and one half copies of the cysteine-rich granulin-epithelin motif. While inappropriate over-expression of the progranulin gene has been associated with many...

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Bibliographic Details
Main Authors: Kay Denis G, Minotti Sandra, Durham Heather D, Cao Mingju, Li Zhi, Malik Suneil, Chitramuthu Babykumari P, Baranowski David C, Ryan Cara L, Shaw Christopher A, Bennett Hugh PJ, Bateman Andrew
Format: Article
Language:English
Published: BMC 2009-10-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/10/130