Heme Oxygenase-1 Protects Hair Cells From Gentamicin-Induced Death

Heme Oxygenase-1 Protects Hair Cells From Gentamicin-Induced Death

Gentamicin ototoxicity can generate free radicals within the inner ear, leading to permanent damage to sensory hair cells (HCs) and eventually hearing loss. The following study examined the alterations of oxidative damage-related genes in the cochlea and important molecules responsible for oxidation...

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Bibliographic Details
Main Authors: Yang Yang, Xin Chen, Keyong Tian, Chaoyong Tian, Liyang Chen, Wenjuan Mi, Qiong Li, Jianhua Qiu, Ying Lin, Dingjun Zha
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
gentamicin
ototoxicity
differential gene expression
HO-1
hair cells
Nrf2
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.783346/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2022.783346/full

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