Docetaxel-loaded human serum albumin (HSA) nanoparticles: synthesis, characterization, and evaluation

Docetaxel-loaded human serum albumin (HSA) nanoparticles: synthesis, characterization, and evaluation

Abstract Background Docetaxel (DTX) is an anticancer drug that is currently formulated with polysorbate 80 and ethanol (50:50, v/v) in clinical use. Unfortunately, this formulation causes hypersensitivity reactions, leading to severe side-effects, which have been primarily attributed to polysorbate...

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Bibliographic Details
Main Authors: Na Qu, Yating Sun, Yujing Li, Fei Hao, Pengyu Qiu, Lesheng Teng, Jing Xie, Yin Gao
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BioMedical Engineering OnLine
Subjects:
Docetaxel
Human serum albumin
Nanoparticles
Self-assembly
Controlled release
Cytotoxicity
Online Access:http://link.springer.com/article/10.1186/s12938-019-0624-7

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http://link.springer.com/article/10.1186/s12938-019-0624-7

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