A genetic replacement system for selection-based engineering of essential proteins

<p>Abstract</p> <p>Background</p> <p>Essential genes represent the core of biological functions required for viability. Molecular understanding of essentiality as well as design of synthetic cellular systems includes the engineering of essential proteins. An impediment...

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Bibliographic Details
Main Authors: Billerbeck Sonja, Panke Sven
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/11/1/110