Poor prognosis, hypomethylation, and immune infiltrates are associated with downregulation of INMT in head and neck squamous cell carcinoma

Poor prognosis, hypomethylation, and immune infiltrates are associated with downregulation of INMT in head and neck squamous cell carcinoma

Background: Indiolethylamine-N-methyltransferase (INMT) is a methyltransferase responsible for transferring methyl groups from methyl donor SAM to its substrate. S-adenosyl-l-methionine (SAM), obtained from the methionine cycle, is a naturally occurring sulfonium compound that is vital to cellular m...

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Bibliographic Details
Main Authors: Kun Cui, Xi Yao, Zhengbo Wei, Yujia yang, Xinli Liu, Zhongheng Huang, Huimin Huo, Jinping Tang, Ying Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Genetics
Subjects:
Indiolethylamine-N-methyltransferase
head and neck squamous cell carcinoma
low expression
poor prognosis
methylation
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.917344/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.917344/full

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