Activation Versus Inhibition of IGF1R: A Dual Role in Breast Tumorigenesis

Historically, the body of literature surrounding the insulin-like growth factor type 1 receptor (IGF1R) has described a largely pro-tumorigenic role in breast cancer cells and in several transgenic or xenograft mouse models of breast cancer. Interestingly, however, more recent evidence has emerged t...

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Bibliographic Details
Main Authors: Joseph J. Bulatowicz, Teresa L. Wood
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.911079/full