The Effects of Two Nrf2 Activators, Bardoxolone Methyl and Omaveloxolone, on Retinal Ganglion Cell Survival during Ischemic Optic Neuropathy

The Effects of Two Nrf2 Activators, Bardoxolone Methyl and Omaveloxolone, on Retinal Ganglion Cell Survival during Ischemic Optic Neuropathy

Nonarteritic anterior ischemic optic neuropathy (NAION) is one of the most common acute optic neuropathies that affect the over 55-year-old population. NAION causes the loss of visual function, and it has no safe and effective therapy. Bardoxolone methyl (methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien...

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Bibliographic Details
Main Authors: Jia-Ying Chien, Yu-Yau Chou, Jhih-Wei Ciou, Fang-Yun Liu, Shun-Ping Huang
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antioxidants
Subjects:
ischemic optic neuropathy
nuclear factor E2-related factor 2
bardoxolone methyl
omaveloxolone
retinal ganglion cell
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/10/9/1466

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https://www.mdpi.com/2076-3921/10/9/1466

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