Identification of the Unwinding Region in the Clostridioides difficile Chromosomal Origin of Replication

Identification of the Unwinding Region in the Clostridioides difficile Chromosomal Origin of Replication

Faithful DNA replication is crucial for viability of cells across all kingdoms. Targeting DNA replication is a viable strategy for inhibition of bacterial pathogens. Clostridioides difficile is an important enteropathogen that causes potentially fatal intestinal inflammation. Knowledge about DNA rep...

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Bibliographic Details
Main Authors: Ana M. Oliveira Paiva, Erika van Eijk, Annemieke H. Friggen, Christoph Weigel, Wiep Klaas Smits
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Microbiology
Subjects:
oriC
Clostridioides difficile
P1 nuclease
unwinding
DnaA
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.581401/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.581401/full

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