Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis

Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis

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Summary: Osteoarthritis (OA) is a prevalent degenerative disease of the elderly. The NRF2 antioxidant system plays a critical role in maintaining redox balance. Mitoquinone (MitoQ) is a mitochondria-targeted antioxidant. This research aimed to determine whether MitoQ alleviated OA and the role of th...

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Bibliographic Details
Main Authors: Liangcai Hou, Genchun Wang, Xiong Zhang, Fan Lu, Jingting Xu, Zhou Guo, Jiamin Lin, Zehang Zheng, Haigang Liu, Yanjun Hou, Kai Sun, Fengjing Guo
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
Subjects:
Orthopedics
Molecular biology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223017248

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http://www.sciencedirect.com/science/article/pii/S2589004223017248

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