Asian-European differentiation of schizophrenia-associated genes driven by admixture and natural selection

Summary: The European-centered genome-wide association studies of schizophrenia (SCZ) may not be well applied to non-European populations. We analyzed 1,592 reported SCZ-associated genes using the public genome data and found an overall higher Asian-European differentiation on the SCZ-associated var...

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Bibliographic Details
Main Authors: Sihan Chen, Die Tang, Lian Deng, Shuhua Xu
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422400782X