Protective effect of L-pipecolic acid on constipation in C57BL/6 mice based on gut microbiome and serum metabolomic

Abstract Background Functional constipation (FC) in children affects their growth, development and quality of life. L-pipecolic acid (L-PA) was decreased in FC children based on gut microbiome and serum metabolomic. In this study, loperamide-induced constipation in mice was used to evaluate the effe...

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Bibliographic Details
Main Authors: Huan Li, Hong-yun Xiao, Li-ping Yuan, Bo Yan, Ying Pan, Ping-ping Tian, Wei-jie Zhang
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Microbiology
Subjects:
Online Access:https://doi.org/10.1186/s12866-023-02880-3