Precision machine learning to understand micro-RNA regulation in neurodegenerative diseases

Precision machine learning to understand micro-RNA regulation in neurodegenerative diseases

Micro-RNAs (miRNAs) are short (∼21 nt) non-coding RNAs that regulate gene expression through the degradation or translational repression of mRNAs. Accumulating evidence points to a role of miRNA regulation in the pathogenesis of a wide range of neurodegenerative (ND) diseases such as, for example, A...

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Bibliographic Details
Main Authors: Lucile Mégret, Cloé Mendoza, Maialen Arrieta Lobo, Emmanuel Brouillet, Thi-Thanh-Yen Nguyen, Olivier Bouaziz, Antoine Chambaz, Christian Néri
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
neurodegenerative disease
miRNA regulation
complex RNA-seq data
machine learning
precision analysis
shape analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.914830/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2022.914830/full

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