Distinctive Toll-like Receptors Gene Expression and Glial Response in Different Brain Regions of Natural Scrapie

Distinctive Toll-like Receptors Gene Expression and Glial Response in Different Brain Regions of Natural Scrapie

Prion diseases are chronic and fatal neurodegenerative diseases characterized by the accumulation of disease-specific prion protein (PrP<sup>Sc</sup>), spongiform changes, neuronal loss, and gliosis. Growing evidence shows that the neuroinflammatory response is a key component of prion d...

Full description

Bibliographic Details
Main Authors: Mirta García-Martínez, Leonardo M. Cortez, Alicia Otero, Marina Betancor, Beatriz Serrano-Pérez, Rosa Bolea, Juan J. Badiola, María Carmen Garza
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
prion
scrapie
toll-like receptors
neuroinflammation
microglia
astrocytes
Online Access:https://www.mdpi.com/1422-0067/23/7/3579

Internet

https://www.mdpi.com/1422-0067/23/7/3579

Similar Items