Generation of Fibrodysplasia ossificans progressiva and control integration free iPSC lines from periodontal ligament fibroblasts

Generation of Fibrodysplasia ossificans progressiva and control integration free iPSC lines from periodontal ligament fibroblasts

Fibrodysplasia ossificans progressiva (FOP) is a very rare devastating heterotopic ossification disorder, classically caused by a heterozygous single point mutation (c.617G>A) in the ACVR1gene, encoding the Bone morphogenetic protein (BMP) type I receptor, also termed activin receptor-like kinase...

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Main Authors: G. Sanchez-Duffhues, H. Mikkers, D. de Jong, K. Szuhai, T.J. de Vries, C. Freund, N. Bravenboer, R.J.J. van Es, J.C. Netelenbos, M.-.J. Goumans, E.M.W. Eekhoff, P. ten Dijke
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506119302697

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http://www.sciencedirect.com/science/article/pii/S1873506119302697

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