Decoy peptides effectively inhibit the binding of SARS-CoV-2 to ACE2 on oral epithelial cells

The entry of SARS-CoV-2 into host cells involves the interaction between the viral spike protein and the human angiotensin-converting enzyme 2 (ACE2) receptor. Given that the spike protein evolves rapidly to evade host immunity, therapeutics that block ACE2 accessibility, such as spike decoys, could...

詳細記述

書誌詳細
主要な著者: Lai-Keng Loi, Cheng-Chieh Yang, Yu-Cheng Lin, Yee-Fun Su, Yi-Chen Juan, Yi-Hsin Chen, Hsiu-Chuan Chang
フォーマット: 論文
言語:English
出版事項: Elsevier 2023-12-01
シリーズ:Heliyon
主題:
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2405844023098225