Dissecting Genetic Control of HLA-DPB1 Expression and Its Relation to Structural Mismatch Models in Hematopoietic Stem Cell Transplantation

Dissecting Genetic Control of HLA-DPB1 Expression and Its Relation to Structural Mismatch Models in Hematopoietic Stem Cell Transplantation

HLA expression levels have been suggested to be genetically controlled by single nucleotide polymorphisms (SNP) in the untranslated regions (UTR), and expression variants have been associated with the outcome of chronic viral infection and hematopoietic stem cell transplantation (HSCT). In particula...

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Bibliographic Details
Main Authors: Thuja Meurer, Esteban Arrieta-Bolaños, Maximilian Metzing, Mona-May Langer, Peter van Balen, J. H. Frederik Falkenburg, Dietrich W. Beelen, Peter A. Horn, Katharina Fleischhauer, Pietro Crivello
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
HLA-DPB1
expression levels
SNP
rs9277534
hematopoietic stem cell transplantation
high risk non-permissive mismatches
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02236/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02236/full

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