Nicotinamide mononucleotide induces lipolysis by regulating ATGL expression via the SIRT1-AMPK axis in adipocytes

Nicotinamide mononucleotide induces lipolysis by regulating ATGL expression via the SIRT1-AMPK axis in adipocytes

Nicotinamide adenine dinucleotide (NAD+) -dependent protein deacetylase SIRT1 plays an important role in the regulation of metabolism. Although the administration of nicotinamide mononucleotide (NMN), a key NAD+ intermediate, has been shown to ameliorate metabolic disorders, such as insulin resistan...

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Bibliographic Details
Main Authors: Yukiko Imi, Reina Amano, Nanaho Kasahara, Yuichiro Obana, Tetsuya Hosooka
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Nicotinamide mononucleotide
Adipose triglyceride lipase
3T3-L1 adipocytes
White adipose tissue
Mice
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823000572

Internet

http://www.sciencedirect.com/science/article/pii/S2405580823000572

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