The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy

The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy

Abstract Autophagy, the process of elimination of cellular components by lysosomal degradation, is essential for animal development and homeostasis. Using the autophagy-dependent Drosophila larval midgut degradation model we identified an autophagy regulator, the RING domain ubiquitin ligase CG14435...

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Bibliographic Details
Main Authors: Shannon Nicolson, Jantina A. Manning, Yoon Lim, Xin Jiang, Erica Kolze, Sonia Dayan, Ruchi Umargamwala, Tianqi Xu, Jarrod J. Sandow, Andrew I. Webb, Sharad Kumar, Donna Denton
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-05834-1

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https://doi.org/10.1038/s42003-024-05834-1

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