Solid Lipid–Polymer Hybrid Nanoplatform for Topical Delivery of siRNA: In Vitro Biological Activity and Permeation Studies

Small interfering RNA (siRNA) molecules have limited transfection efficiency and stability, necessitating the use of delivery systems to be effective in gene knockdown therapies. In this regard, lipid–polymeric nanocarriers have emerged as a promising class of nanoparticles for siRNA delivery, parti...

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Bibliographic Details
Main Authors: Margarete Moreno de Araujo, Livia Neves Borgheti-Cardoso, Fabíola Garcia Praça, Priscyla Daniely Marcato, Maria Vitória Lopes Badra Bentley
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Journal of Functional Biomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4983/14/7/374