Modeling and Analysis of HIV-1 Pol Polyprotein as a Case Study for Predicting Large Polyprotein Structures

Modeling and Analysis of HIV-1 Pol Polyprotein as a Case Study for Predicting Large Polyprotein Structures

Acquired immunodeficiency syndrome (AIDS) is caused by human immunodeficiency virus (HIV). HIV protease, reverse transcriptase, and integrase are targets of current drugs to treat the disease. However, anti-viral drug-resistant strains have emerged quickly due to the high mutation rate of the virus,...

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Bibliographic Details
Main Authors: Ming Hao, Tomozumi Imamichi, Weizhong Chang
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
HIV-1 Pol structure
immature protein structure modeling
computational structural biology
domain assembly
loop modeling
homology modeling
Online Access:https://www.mdpi.com/1422-0067/25/3/1809

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https://www.mdpi.com/1422-0067/25/3/1809

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