INFLUENCE OF THE IMIQUIMOD ON THE INTERFERON PRODUCTION AND TREATMENT OF THE EXPERIMENTAL HERPES SIMPLEX VIRUS INFECTION

Background. Imiquimod is an imidazole derivative acting as an immunomodulator on the level of innate and adaptive immune system. Our objective was to evaluate the antiviral activity of generically reproduced imiquimod administered subcutaneously in mice and intravaginally in guinea pigs against herp...

Full description

Bibliographic Details
Main Authors: V. S. Smirnov, S. V. Petlenko
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2017-06-01
Series:Вопросы вирусологии
Subjects:
Online Access:https://virusjour.crie.ru/jour/article/viewFile/154/64