Effects of poly (ADP-ribose) polymerase inhibitor treatment on the repair process of ischemic acute kidney injury

Effects of poly (ADP-ribose) polymerase inhibitor treatment on the repair process of ischemic acute kidney injury

Abstract Excessive activation of poly (ADP-ribose) polymerase (PARP) contributes to ischemic acute kidney injury (AKI). PARP inhibition has been shown to be beneficial in renal ischemia–reperfusion injury (IRI) in the early phase, but its role in the repair process remains unclear. The effects of JP...

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Main Authors: Junseok Jeon, Kyungho Lee, Hye Ryoun Jang, Kyeong Eun Yang, Cheol-Jung Lee, Hyeonju Ahn, Woong-Yang Park, Jung Eun Lee, Ghee Young Kwon, Yoon-Goo Kim, Wooseong Huh
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50630-2

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https://doi.org/10.1038/s41598-023-50630-2

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