Promoter strength driving TetR determines the regulatory properties of Tet-controlled expression systems.

Bacteria frequently rely on transcription repressors and activators to alter gene expression patterns in response to changes in the surrounding environment. Tet repressor (TetR) is a paradigm transcription factor that senses the environmental state by binding small molecule effectors, the tetracycli...

Full description

Bibliographic Details
Main Authors: Christiane Georgi, Julia Buerger, Wolfgang Hillen, Christian Berens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3407185?pdf=render