iPhemap: an atlas of phenotype to genotype relationships of human iPSC models of neurological diseases

iPhemap: an atlas of phenotype to genotype relationships of human iPSC models of neurological diseases

Abstract Disease modeling with induced pluripotent stem cells (iPSCs) is creating an abundance of phenotypic information that has become difficult to follow and interpret. Here, we report a systematic analysis of research practices and reporting bias in neurological disease models from 93 published...

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Bibliographic Details
Main Authors: Ethan W Hollingsworth, Jacob E Vaughn, Josh C Orack, Chelsea Skinner, Jamil Khouri, Sofia B Lizarraga, Mark E Hester, Fumihiro Watanabe, Kenneth S Kosik, Jaime Imitola
Format: Article
Language:English
Published: Springer Nature 2017-10-01
Series:EMBO Molecular Medicine
Subjects:
Alzheimer's disease
iPSCs
neurogenetics
neurological diseases
phenogenetics
Online Access:https://doi.org/10.15252/emmm.201708191

Internet

https://doi.org/10.15252/emmm.201708191

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