Development of a Polymeric Pharmacological Nanocarrier System as a Potential Therapy for Spinocerebellar Ataxia Type 7

Development of a Polymeric Pharmacological Nanocarrier System as a Potential Therapy for Spinocerebellar Ataxia Type 7

Spinocerebellar ataxia type 7 (SCA7) is an autosomal-dominant inherited disease characterized by progressive ataxia and retinal degeneration. SCA7 belongs to a group of neurodegenerative diseases caused by an expanded CAG repeat in the disease-causing gene, resulting in aberrant polyglutamine (polyQ...

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Bibliographic Details
Main Authors: Fabiola V. Borbolla-Jiménez, Ian A. García-Aguirre, María Luisa Del Prado-Audelo, Oscar Hernández-Hernández, Bulmaro Cisneros, Gerardo Leyva-Gómez, Jonathan J. Magaña
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
nanotechnology
pharmacological treatment
polymeric nanocarrier
polyQ aggregation
rapamycin
spinocerebellar ataxia type 7
Online Access:https://www.mdpi.com/2073-4409/12/23/2735

Internet

https://www.mdpi.com/2073-4409/12/23/2735

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