miR-142-5p Encapsulated by Serum-Derived Extracellular Vesicles Protects against Acute Lung Injury in Septic Rats following Remote Ischemic Preconditioning via the PTEN/PI3K/Akt Axis

miR-142-5p Encapsulated by Serum-Derived Extracellular Vesicles Protects against Acute Lung Injury in Septic Rats following Remote Ischemic Preconditioning via the PTEN/PI3K/Akt Axis

This study intends to investigate the effects of miR-142-5p encapsulated by serum-derived extracellular vesicles (EVs) on septic acute lung injury (ALI) following remote ischemic preconditioning (RIPC) through a PTEN-involved mechanism. ALI was induced in rats by lipopolysaccharide (LPS) injection,...

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Bibliographic Details
Main Authors: Wenliang Zhu, Xiaopei Huang, Shi Qiu, Lingxiao Feng, Yue Wu, Huanzhang Shao
Format: Article
Language:English
Published: Karger Publishers 2022-05-01
Series:Journal of Innate Immunity
Subjects:
acute lung injury
sepsis
remote ischemic preconditioning
extracellular vesicles
mir-142-5p
phosphatase and tensin homologue deleted on chromosome 10
Online Access:https://www.karger.com/Article/FullText/522231

Internet

https://www.karger.com/Article/FullText/522231

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