miR-142-5p Encapsulated by Serum-Derived Extracellular Vesicles Protects against Acute Lung Injury in Septic Rats following Remote Ischemic Preconditioning via the PTEN/PI3K/Akt Axis

miR-142-5p Encapsulated by Serum-Derived Extracellular Vesicles Protects against Acute Lung Injury in Septic Rats following Remote Ischemic Preconditioning via the PTEN/PI3K/Akt Axis

This study intends to investigate the effects of miR-142-5p encapsulated by serum-derived extracellular vesicles (EVs) on septic acute lung injury (ALI) following remote ischemic preconditioning (RIPC) through a PTEN-involved mechanism. ALI was induced in rats by lipopolysaccharide (LPS) injection,...

Full description

Bibliographic Details
Main Authors:	Wenliang Zhu, Xiaopei Huang, Shi Qiu, Lingxiao Feng, Yue Wu, Huanzhang Shao
Format:	Article
Language:	English
Published:	Karger Publishers 2022-05-01
Series:	Journal of Innate Immunity
Subjects:	acute lung injury sepsis remote ischemic preconditioning extracellular vesicles mir-142-5p phosphatase and tensin homologue deleted on chromosome 10
Online Access:	https://www.karger.com/Article/FullText/522231

Similar Items

Dose-Dependent Protective Effect of Bisperoxovanadium against Acute Cerebral Ischemia in a Rat Model of Ischemia/Reperfusion Injury
by: Heng-Li Tian, et al.
Published: (2013-06-01)

PTEN Immunoexpression in Atypical Endometrial Hyperplasia and Endometrioid Endometrial Carcinoma: A Research Protocol
by: Garima Akhil chandrakar, et al.
Published: (2023-07-01)

RETRACTED ARTICLE: Inhibited MicroRNA-301 Restrains Angiogenesis and Cell Growth in Esophageal Squamous Cell Carcinoma by Elevating PTEN
by: Bin Wang, et al.
Published: (2021-01-01)

Effect of miR-26a on drug resistance of chronic lymphocytic leukemia cells by regulating PTEN gene
by: MAO Hong-bin, HE Ming
Published: (2021-06-01)

Effect of fenofibrate on the expression of miR-26a-5p/PTEN in retinal neurons of diabetic mice
by: Tang Derong, et al.
Published: (2024-01-01)

The progress of research into pseudophosphatases
by: Deqiang Liu, et al.
Published: (2022-08-01)

PTEN inhibitor bisperoxovanadium protects against noise-induced hearing loss
by: Bei Fan, et al.
Published: (2023-01-01)

Immunohistochemical and molecular profiles of heterogeneous components of metaplastic breast cancer: a squamous cell carcinomatous component was distinct from a spindle cell carcinomatous component
by: Takahiro Suzuki, et al.
Published: (2024-04-01)

β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN
by: Guang Xia, et al.
Published: (2023-05-01)

PTEN and Other PtdIns(3,4,5)P<sub>3</sub> Lipid Phosphatases in Breast Cancer
by: Mariah P. Csolle, et al.
Published: (2020-12-01)

Association of Phosphatase and Tensin Homologue-induced Putative Kinase 1 with Refractory Diabetic Wound Healing: a Review
by: YANG Jiaqi, ZHANG Peihua, HUANG Haili
Published: (2023-05-01)

Retroperitoneal hamartoma mimicking angiomyolipoma: a case report and review of literature
by: Lesheng Huang, et al.
Published: (2022-05-01)

Immune Landscape in PTEN-Related Glioma Microenvironment: A Bioinformatic Analysis
by: Alice Giotta Lucifero, et al.
Published: (2022-04-01)

The Role of the PTEN Tumor Suppressor Gene and Its Anti-Angiogenic Activity in Melanoma and Other Cancers
by: Jacqueline Maphutha, et al.
Published: (2024-02-01)

Editorial: Deciphering and targeting the mTOR pathway in hematologic malignancies
by: Luca Lo Nigro
Published: (2023-12-01)

Editorial: Thyroid nodules and tumors in childhood
by: Luisa de Sanctis, et al.
Published: (2023-10-01)

PTEN, a Barrier for Proliferation and Metastasis of Gastric Cancer Cells: From Molecular Pathways to Targeting and Regulation
by: Milad Ashrafizadeh, et al.
Published: (2020-08-01)

Alkannin exerts antitumor properties in cutaneous squamous cell carcinoma by inducing apoptosis and shifting the M1/M2 polarization of tumor‐associated macrophages by upregulating PTEN
by: Zhong‐Zhao Zhang, et al.
Published: (2023-01-01)

Phosphatase and tensin analog expression in arterial atherosclerotic lesions
by: Elancheran Muthalagan, et al.
Published: (2014-01-01)

miR-499a-5p alleviates hypoxic damage of pheochromocytoma cells through targeting at Pten
by: ZHANG Li-yang, SUN Jun, CHEN Di
Published: (2022-12-01)

PTEN-regulated alternative splicing of FoxM1 affects tumor cell migration
by: WANG Xiaoling, et al.
Published: (2023-11-01)

Phosphatase and Tensin Homolog (PTEN) of Japanese Flounder—Its Regulation by miRNA and Role in Autophagy, Apoptosis and Pathogen Infection
by: Wenrui Li, et al.
Published: (2020-10-01)

Dysregulation of gene expression of PTEN and AKT signaling pathway in patients of ovarian cancer: A pilot study
by: Laraib Zara, et al.
Published: (2023-01-01)

The c-Myc/miR17-92/PTEN Axis Tunes PI3K Activity to Control Expression of Recombination Activating Genes in Early B Cell Development
by: David Benhamou, et al.
Published: (2018-11-01)

PGE2 inhibits neutrophil phagocytosis through the EP2R–cAMP–PTEN pathway
by: Zixuan Wang, et al.
Published: (2022-07-01)

MicroRNAs as Predictors of Future Uterine Malignancy in Endometrial Hyperplasia without Atypia
by: Chiao-Yun Lin, et al.
Published: (2022-02-01)

Comparing Protection of Remote Limb with Resveratrol Preconditioning following Rodent Subarachnoid Hemorrhage
by: Sebastian Koch, et al.
Published: (2022-04-01)

Activation of PKG and Akt Is Required for Cardioprotection by Ramelteon-Induced Preconditioning and Is Located Upstream of mKCa-Channels
by: Carolin Torregroza, et al.
Published: (2020-04-01)

Research hotspots and frontiers of preconditioning in cerebral ischemia: A bibliometric analysis
by: Long Zhang, et al.
Published: (2024-02-01)

Effects Of Ischemic Preconditioning On The Renal Ischemia- Reperfusion Injury
by: Anyamanesh S, et al.
Published: (2003-07-01)

Development of a Genetically Engineered Mouse Model Recapitulating LKB1 and PTEN Deficiency in Gastric Cancer Pathogenesis
by: Kuan-Te Fang, et al.
Published: (2023-12-01)

Low-Dose Ammonium Preconditioning Enhances Endurance in Submaximal Physical Exercises
by: Igor Mindukshev, et al.
Published: (2021-02-01)

Modulation of Remote Ischemic Preconditioning by Proinflammatory Cytokines in Renal Transplant Recipients
by: Homero Zapata-Chavira, et al.
Published: (2019-01-01)

Expression pattern of phosphatase and tensin homolog and epidermal growth factor receptor in patients with brain tumor
by: Ananthan Raghotham, et al.
Published: (2023-01-01)

Recombination between T-DNA insertions to cause chromosomal deletions in Arabidopsis is a rare phenomenon
by: John F. Seagrist, et al.
Published: (2018-07-01)

Cervical Spine Malformations Associated With a 5q34-5q35.2 Micro-interstitial Deletion: A Case Report
by: Heewon Lee, et al.
Published: (2018-12-01)

TADALAFIL AS AN AGENT OF PHARMACOLOGICAL PRECONDITIONING IN ISCHEMIC – REPERFUSION BRAIN INJURY
by: Olga Martynova
Published: (2017-09-01)

Exploring the Metabolic and Endocrine Preconditioning Associated with Thyroid Disorders: Risk Assessment and Association with Acne Severity
by: Alexa Florina Bungau, et al.
Published: (2024-01-01)

Average Nutrient Content and Bulk Price of Byproduct Feeds Commonly Available to Florida Cattle Producers
by: John D. Arthington
Published: (2003-06-01)

Southern Green Stink Bug, Nezara viridula (Linnaeus) (Insecta: Hemiptera: Pentatomidae)
by: Jason M. Squitier
Published: (2011-01-01)