LncRNA LINK‐A Remodels Tissue Inflammatory Microenvironments to Promote Obesity

LncRNA LINK‐A Remodels Tissue Inflammatory Microenvironments to Promote Obesity

Abstract High‐fat diet (HFD)‐induced obesity is a crucial risk factor for metabolic syndrome, mainly due to adipose tissue dysfunctions associated with it. However, the underlying mechanism remains unclear. This study has used genetic screening to identify an obesity‐associated human lncRNA LINK‐A a...

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Bibliographic Details
Main Authors: Yu Chen, Hui Chen, Ying Wang, Fangzhou Liu, Xiao Fan, Chengyu Shi, Xinwan Su, Manman Tan, Yebin Yang, Bangxing Lin, Kai Lei, Lei Qu, Jiecheng Yang, Zhipeng Zhu, Zengzhuang Yuan, Shanshan Xie, Qinming Sun, Dante Neculai, Wei Liu, Qingfeng Yan, Xiang Wang, Jianzhong Shao, Jian Liu, Aifu Lin
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
HIF1α
high‐fat diet
inflammatory microenvironment
LncRNA
obesity
therapeutic target
Online Access:https://doi.org/10.1002/advs.202303341

Internet

https://doi.org/10.1002/advs.202303341

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