Understanding signatures of positive natural selection in human zinc transporter genes

Abstract Zinc is an essential micronutrient with a tightly regulated systemic and cellular homeostasis. In humans, some zinc transporter genes (ZTGs) have been previously reported as candidates for strong geographically restricted selective sweeps. However, since zinc homeostasis is maintained by th...

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Bibliographic Details
Main Authors: Ana Roca-Umbert, Rocio Caro-Consuegra, Diego Londono-Correa, Gabriel Felipe Rodriguez-Lozano, Ruben Vicente, Elena Bosch
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08439-y