Synthesis, biological evaluation and docking studies of 1,2,4-oxadiazole linked 5-fluorouracil derivatives as anticancer agents

Synthesis, biological evaluation and docking studies of 1,2,4-oxadiazole linked 5-fluorouracil derivatives as anticancer agents

Abstract Background 1,2,4-oxadiazole derivatives exhibited significant anti-cancer activity when they were evaluated, against human cancer cell lines. They also showed anti-inflammatory, analgesic, diabetic, immunosuppressive, α,β3-receptor antagonist, antimicrobial, anti-helminthic, histamine-H3 an...

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Bibliographic Details
Main Authors: Ravi Kumar Bommera, Shashikala Kethireddy, Rajeshwar Reddy Govindapur, Laxminarayana Eppakayala
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Chemistry
Subjects:
5-Fluorouracil
Ataluren
Pyrimidine
Oxadiazole and anticancer activity
Online Access:https://doi.org/10.1186/s13065-021-00757-y

Internet

https://doi.org/10.1186/s13065-021-00757-y

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