Improved Dissolution and Oral Bioavailability of Valsartan Using a Solidified Supersaturable Self-Microemulsifying Drug Delivery System Containing Gelucire<sup>®</sup> 44/14

Improved Dissolution and Oral Bioavailability of Valsartan Using a Solidified Supersaturable Self-Microemulsifying Drug Delivery System Containing Gelucire<sup>®</sup> 44/14

To improve the dissolution and oral bioavailability of valsartan (VST), we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMED) composed of Capmul<sup>&#174;</sup> MCM (oil), Tween<sup>&#174;</sup> 80 (surfactant), Transcutol<s...

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Bibliographic Details
Main Authors: Dong Jun Shin, Bo Ram Chae, Yoon Tae Goo, Ho Yub Yoon, Chang Hyun Kim, Se Il Sohn, Dongho Oh, Ahram Lee, Seh Hyon Song, Young Wook Choi
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Pharmaceutics
Subjects:
Valsartan
SMEDDS
Gelucire<sup>®</sup> 44/14
solidification
bioavailability
Online Access:https://www.mdpi.com/1999-4923/11/2/58

Internet

https://www.mdpi.com/1999-4923/11/2/58

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