The role of oxidative post-translational modifications in type 1 diabetes pathogenesis

The role of oxidative post-translational modifications in type 1 diabetes pathogenesis

The pathogenesis of type 1 diabetes (T1D) involves a complex interplay of genetic predisposition, immune processes, and environmental factors, leading to the selective destruction of pancreatic beta-cells by the immune system. Emerging evidence suggests that intrinsic beta-cell factors, including ox...

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Detalles Bibliográficos
Autores principales: Ghadeer Alhamar, Chiara Vinci, Valentina Franzese, Flavia Tramontana, Nelig Le Goux, Johnny Ludvigsson, Ahuva Nissim, Rocky Strollo
Formato: Artículo
Lenguaje:English
Publicado: Frontiers Media S.A. 2025-02-01
Colección:Frontiers in Immunology
Materias:
post-translational modifications
type 1 diabetes
oxidative stress
neoepitopes
autoimmunity
insulin
Acceso en línea:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1537405/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2025.1537405/full

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