Beyond NF-κB activation: nuclear functions of IκB kinase α

Beyond NF-κB activation: nuclear functions of IκB kinase α

<p>Abstract</p> <p>IκB kinase (IKK) complex, the master kinase for NF-κB activation, contains two kinase subunits, IKKα and IKKβ. In addition to mediating NF-κB signaling by phosphorylating IκB proteins during inflammatory and immune responses, the activation of the IKK complex als...

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Bibliographic Details
Main Authors: Huang Wei-Chien, Hung Mien-Chie
Format: Article
Language:English
Published: BMC 2013-01-01
Series:Journal of Biomedical Science
Subjects:
Nuclear IKKα
NF-κB
Gene transcription
Tumor progression
Online Access:http://www.jbiomedsci.com/content/20/1/3

Internet

http://www.jbiomedsci.com/content/20/1/3

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