Deficiency of Trex1 leads to spontaneous development of type 1 diabetes

Deficiency of Trex1 leads to spontaneous development of type 1 diabetes

Abstract Background Type 1 diabetes is believed to be an autoimmune condition, characterized by destruction of insulin-producing cells, due to the detrimental inflammation in pancreas. Growing evidences have indicated the important role of type I interferon in the development of type 1 diabetes. Met...

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Bibliographic Details
Main Authors: Jiang-Man Zhao, Zhi-Hui Su, Qiu-Ying Han, Miao Wang, Xin Liu, Jing Li, Shao-Yi Huang, Jing Chen, Xiao-Wei Li, Xia-Ying Chen, Zeng-Lin Guo, Shuai Jiang, Jie Pan, Tao Li, Wen Xue, Tao Zhou
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Nutrition & Metabolism
Subjects:
TREX1
Type 1 diabetes
Type I interferon
Online Access:https://doi.org/10.1186/s12986-023-00777-6

Internet

https://doi.org/10.1186/s12986-023-00777-6

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