Dysregulation of Lymphatic Endothelial VEGFR3 Signaling in Disease

Dysregulation of Lymphatic Endothelial VEGFR3 Signaling in Disease

Vascular endothelial growth factor (VEGF) receptor 3 (VEGFR3), a receptor tyrosine kinase encoded by the <i>FLT4</i> gene, plays a significant role in the morphogenesis and maintenance of lymphatic vessels. Under both normal and pathologic conditions, VEGF-C and VEGF-D bind VEGFR3 on the...

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Bibliographic Details
Main Authors: Kevin Kuonqui, Adana-Christine Campbell, Ananta Sarker, Arielle Roberts, Bracha L. Pollack, Hyeung Ju Park, Jinyeon Shin, Stav Brown, Babak J. Mehrara, Raghu P. Kataru
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
lymphatics
endothelial cells
lymphangiogenesis
cancer
inflammation
VEGFR-3
Online Access:https://www.mdpi.com/2073-4409/13/1/68

Internet

https://www.mdpi.com/2073-4409/13/1/68

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