Elucidating Cyathula Officinals' mechanism in osteoarthritis treatment: Network pharmacology and empirical evidence on anti-inflammatory actions

Elucidating Cyathula Officinals' mechanism in osteoarthritis treatment: Network pharmacology and empirical evidence on anti-inflammatory actions

In this study, we explored the therapeutic potential of Cyathula Officinals (CNX) in Knee Osteoarthritis (KOA) treatment. Utilizing network pharmacology and in vitro experiments, we identified active ingredients, action targets and pathways in CNX. Our analysis, integrating databases like TCMSP, Swi...

Full description

Bibliographic Details
Main Authors: Zhicheng Yao, Fengping Gan, Yuqing Zeng, Litong Ren, Yirong Zeng
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Cyathula Officinals
Knee osteoarthritis
NF-κB pathway
MAPK pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024040301

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024040301

Similar Items