Characterization of interstitial Cajal progenitors cells and their changes in Hirschsprung's disease.

Interstitial cells of Cajal (ICC) are critical to gastrointestinal motility. The phenotypes of ICC progenitors have been observed in the mouse gut, but whether they exist in the human colon and what abnormal changes in their quantity and ultrastructure are present in Hirschsprung's disease (HSC...

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Bibliographic Details
Main Authors: Zhi-Hua Chen, Yong-Chang Zhang, Wei-Fang Jiang, Cissy Yang, Gang-Ming Zou, Yu Kong, Wei Cai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3901676?pdf=render