Integrating cell interaction with transcription factors to obtain a robust gene panel for prognostic prediction and therapies in cholangiocarcinoma

Integrating cell interaction with transcription factors to obtain a robust gene panel for prognostic prediction and therapies in cholangiocarcinoma

Objective: The efficacy of immunotherapy for cholangiocarcinoma (CCA) is blocked by a high degree of tumor heterogeneity. Cell communication contributes to heterogeneity in the tumor microenvironment. This study aimed to explore critical cell signaling and biomarkers induced via cell communication d...

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Bibliographic Details
Main Authors: Tingjie Wang, Chuanrui Xu, Dan Xu, Xiaofei Yang, Yaxin Liu, Xiujuan Li, Zihang Li, Ningxin Dang, Yi Lv, Zhijing Zhang, Lei Li, Kai Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Genetics
Subjects:
cell communication
single cell RNAseq
transcript factor
cholangiocarcinoma
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.981145/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.981145/full

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