Genome‐wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

Genome‐wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

Forkhead box O (FOXO) transcription factors are key players in diverse cellular processes affecting tumorigenesis, stem cell maintenance and lifespan. To gain insight into the mechanisms of FOXO‐regulated target gene expression, we studied genome‐wide effects of FOXO3 activation. Profiling RNA polym...

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Bibliographic Details
Main Authors: Astrid Eijkelenboom, Michal Mokry, Elzo de Wit, Lydia M Smits, Paulien E Polderman, Miranda H van Triest, Ruben van Boxtel, Almut Schulze, Wouter de Laat, Edwin Cuppen, Boudewijn M T Burgering
Format: Article
Language:English
Published: Springer Nature 2013-01-01
Series:Molecular Systems Biology
Subjects:
enhancer
FOXO
initiation
RNA pol II
transcription
Online Access:https://doi.org/10.1038/msb.2012.74

Internet

https://doi.org/10.1038/msb.2012.74

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