The renoprotective effects of Heme Oxygenase-1 during contrast-induced acute kidney injury in preclinical diabetic models

The renoprotective effects of Heme Oxygenase-1 during contrast-induced acute kidney injury in preclinical diabetic models

OBJECTIVES: Contrast-induced acute kidney injury (CI-AKI) is an important clinical problem that can be aggravated by diabetes mellitus, a major risk factor. However, heme oxygenase-1 (HO-1), a promising therapeutic target, can exert antioxidant effects against CI-AKI. Thus, we investigated the role...

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Bibliographic Details
Main Authors: Cassiane Dezoti da Fonseca, Mirian Watanabe, Sheila Marques Fernandes Couto, Alef Aragão Carneiro dos Santos, Fernanda Teixeira Borges, Maria de Fatima Fernandes Vattimo
Format: Article
Language:English
Published: Elsevier España 2021-10-01
Series:Clinics
Subjects:
Heme Oxygenase-1
Nephrotoxicity
Oxidative Stress
Diabetes Mellitus
Iodinated Contrast
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322021000100321&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322021000100321&tlng=en

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