Metformin suppresses NFE2L1 pathway activation to inhibit gap junction beta protein expression in NSCLC

Metformin suppresses NFE2L1 pathway activation to inhibit gap junction beta protein expression in NSCLC

Abstract Objective Non‐small‐cell lung cancer (NSCLC) is a deadly form of cancer that exhibits extensive intercellular communication which contributed to chemoradiotherapy resistance. Recent evidence suggests that arrange of key proteins are involved in lung cancer progression, including gap junctio...

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Bibliographic Details
Main Authors: Shuo Yu, Hui Ren, Tingting Liu, Xiaoyan Han, Hui Guo, Qian Ning, Yang Li, Hong Zhou, Mingwei Chen, Tinghua Hu
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Cancer Medicine
Subjects:
gap junction proteins
metformin
NFE2L1
NSCLC
prognosis
Online Access:https://doi.org/10.1002/cam4.7021

Internet

https://doi.org/10.1002/cam4.7021

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