Skeletal muscle as an experimental model of choice to study tissue aging and rejuvenation

Abstract Skeletal muscle is among the most age-sensitive tissues in mammal organisms. Significant changes in its resident stem cells (i.e., satellite cells, SCs), differentiated cells (i.e., myofibers), and extracellular matrix cause a decline in tissue homeostasis, function, and regenerative capaci...

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Bibliographic Details
Main Authors: Jessy Etienne, Chao Liu, Colin M. Skinner, Michael J. Conboy, Irina M. Conboy
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Skeletal Muscle
Subjects:
Online Access:https://doi.org/10.1186/s13395-020-0222-1