Multi-tumor analysis of cancer-stroma interactomes of patient-derived xenografts unveils the unique homeostatic process in renal cell carcinomas

Multi-tumor analysis of cancer-stroma interactomes of patient-derived xenografts unveils the unique homeostatic process in renal cell carcinomas

Summary: The patient-derived xenograft (PDX) model is a versatile tool used to study the tumor microenvironment (TME). However, limited studies have described multi-tumor PDX screening strategies to detect hub regulators during cancer-stroma interaction. Transcriptomes of cancer (human) and stroma (...

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Bibliographic Details
Main Authors: Kuniyo Sueyoshi, Daisuke Komura, Hiroto Katoh, Asami Yamamoto, Takumi Onoyama, Tsuyoshi Chijiwa, Takayuki Isagawa, Mariko Tanaka, Hiroshi Suemizu, Masato Nakamura, Yohei Miyagi, Hiroyuki Aburatani, Shumpei Ishikawa
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:iScience
Subjects:
Cancer systems biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221012918

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http://www.sciencedirect.com/science/article/pii/S2589004221012918

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